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KMID : 0359719950130010084
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Journal of the Korean Neurological Association
1995 Volume.13 No. 1 p.84 ~ p.90
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MR Imagings of Chronic Acquired Hepatic Failure
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강경수
김상윤/황성희/고운산/이현미/권기한/이병철
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Abstract
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Neuroimaging of the brain is useful diagnostic evaluation of patients with hepatic encephalopathy insofar as it is able to exclude other causes of abnormal mental status. Recently, changes of basal ganglia on MRI characterized by increased signal
intensity on T1-weighted images were reported in patients with liver cirrhosis. Signal abnormality involves mainly the globus pallidus and seems to be specific for aptients with chronic liver disease. Its pathogenesis and significance are
obscure,
and
no pathological reports have been made. We experienced 3 cases of ch-ronic acquired hepatic failure whose MRI showed increased signal in-tensity in the basal ganglia on T1-weighted imaging. Our findings su-ggest that bassal ganglia signal
abnormality
could arise as a marker of brain impairment related to deposition of an unidentified paramagnetic substance or altered intracellular water relaxation.
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KEYWORD
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